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| Compound | EGFR inhibition IC50 ± SEM (nM) | HER-2 inhibition IC50 ± SEM (nM) |
|---|---|---|
| 3e | 79 ± 5 | 39 ± 2 |
| 5a | 71 ± 4 | 31 ± 2 |
| 5b | 85 ± 5 | 47 ± 3 |
| 5d | 93 ± 5 | 53 ± 3 |
| Erlotinib | 80 ± 5 | — |
| Lapatinib | — | 26 ± 1 |
