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. 2024 Oct 21;14(45):32978–32991. doi: 10.1039/d4ra06394e

Apoptotic potentials of compounds 3e and 5a.

Compd no. Caspase-3 Caspase-8 Bax Bcl-2
Conc. (pg ml−1) Fold change Conc. (ng ml−1) Fold change Conc. (pg ml−1) Fold change Conc. (ng ml−1) Fold reduction
3e 587 ± 5 9 1.65 ± 0.20 19 316 ± 3 35 0.84 6
5a 710 ± 6 11 1.70 ± 0.15 21 350 ± 3 39 0.62 8
Staurosporine 465 ± 4 7 1.60 ± 0.10 18 288 ± 2 32 1.00 5
Control 65 1 0.09 1 9 1 5.00 1