Table 2.
Characteristics of index hospitalization among individuals with and without sepsis
| Variable | Prior to weighting | After weighting | ||||
|---|---|---|---|---|---|---|
| Sepsis N = 79, 065 | Non-Sepsis N = 847, 992 | Standardized Difference | Sepsis N = 888,513 | Non-Sepsis N = 928,323 | Weighted Standardized Difference | |
| Hospital Size, n (%) | ||||||
| Teaching | 20,511 (25.9%) | 279,789 (33.0%) | 0.16 | 27.41% | 32.85% | 0.119 |
| Community ≥ 100 beds | 40,551 (51.3%) | 424,804 (50.1%) | 0.02 | 51.30% | 50.06% | 0.025 |
| Community < 100 beds | 16,758 (21.2%) | 128,145 (15.1%) | 0.16 | 19.77% | 15.28% | 0.118 |
| Missing information | 1,245 (1.6%) | 15,254 (1.8%) | 0.02 | 1.51% | 1.81% | 0.023 |
| Type of hospitalization, n (%) | ||||||
|
Medical (including mental health) |
47,903 (60.6%) | 287,902 (34.0%) | 0.55 | 60.51% | 34.61% | 0.537 |
| Surgical | 8,159 (10.3%) | 291,135 (34.3%) | 0.6 | 10.76% | 33.89% | 0.578 |
| Not categorized | 23,003 (29.1%) | 268,955 (31.7%) | 0.06 | 28.74% | 31.51% | 0.060 |
| Charlson score of index hospitalization, mean ± SD, median (IQR) |
1.51 ± 1.68 1 (0–2) |
0.89 ± 1.46 0 (0–1) |
0.39 0.52 |
1.24 | 0.92 | 0.207 |
| Length of Stay (days), mean ± SD, median (IQR) |
14.79 ± 28.89 7 (4–15) |
4.88 ± 9.91 3 (1–5) |
0.46 0.96 |
12.82 | 5.05 | 0.381 |
| ICU Admission during index admission, n (%) | 16,750 (21.2%) | 121,991 (14.4%) | 0.18 | 17.57% | 15.03% | 0.069 |
| ICU length of stay (days), mean ± SD, median (IQR) |
8.84 ± 17.42 5 (2–9) |
3.14 ± 4.96 2 (1–4) |
0.45 0.81 |
9.95 | 3.15 | 0.510 |
| Mechanical ventilation, n (%) | 8,301 (10.5%) | 35,006 (4.1%) | 0.25 | 9.41% | 4.26% | 0.205 |
| ECLS during index admission, n (%) | 151 (0.2%) | 354 (0.0%) | 0.04 | 0.21% | 0.04% | 0.046 |
| Discharge location, n (%) | ||||||
| Transferred to acute inpatient facility | 955 (1.2%) | 6,730 (0.8%) | 0.04 | 1.19% | 0.81% | 0.038 |
|
Transferred to long-term care, continuing care, or supportive housing |
17,867 (22.6%) | 64,046 (7.6%) | 0.43 | 14.51% | 8.37% | 0.194 |
| Discharged home | 59,559 (75.3%) | 767,584 (90.5%) | 0.41 | 82.80% | 89.72% | 0.202 |
| Discharged other [e.g., AMA, on pass] | 684 (0.9%) | 9,632 (1.1%) | 0.03 | 1.51% | 1.11% | 0.035 |
| Cost of index hospitalization, Mean ± SD, Median (IQR) |
$18,434.82 ± $37,142.81 $8,713 ($5,486—$16,687) |
$7,788.10 ± $10,962.88 $5,212 ($3,269—$8,372) |
0.39 0.78 |
$17,394.6 | $7924.88 | 0.343 |
SD Standard Deviation, IQR Interquartile Range, ECLS Extracorporeal life support
aThis includes invasive or non-invasive mechanical ventilation