. 2024 Oct 21;25:698. doi: 10.1186/s13063-024-08474-2

Table 5.

Table of events

		Study day
	Enrollment	1	2	3–6	7	8–27	28	90
Eligibility
Inclusion/exclusion	X
Informed consent	X
Randomization
Randomization		X
Post-randomization
Study drug administration		X	X^a
Case report forms	X	X	X		X		X	X
Bedside data element for SOFA score (vitals, GCS)	X				X^b
Biospecimen sampling	X				X^b		X^b
Rectal swab	X
Zubrod performance	X				X^b		X^b
SF-12	X				X^b		X^b
SnC measurement	X				X^b		X^b
CRR SOFA calculation	X				X^b
Adverse event assessment		X	X	X^b	X^b	X^b	X^b	X^b
Survival and rehospitalization assessment							X^b	X^b

^aParticipants allocated to single-day Fisetin dosing will receive placebo on day 2 to preserve blinding

^bPerformed at home via phone or mobile phlebotomy, as relevant, if already discharged