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. Author manuscript; available in PMC: 2024 Oct 21.
Published in final edited form as: Nat Methods. 2021 Dec 2;18(12):1524–1531. doi: 10.1038/s41592-021-01331-z

Fig. 4 |. Robustness of MS/MS similarity algorithms against random noise ions.

Fig. 4 |

ROC curves for 43 different spectral similarity algorithms applied to the small-molecule NIST20 database with randomly added noise ions. a, robustness against ten added noise ions with different total noise intensities. b, robustness against 1–30 additional noise ions with a total sum intensity equal to the sum intensity of the MS/MS spectrum of each test molecule.