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Therapeutic impact of PPARγ-modRNA in a murine full-thickness skin defect model. Gross observations and photographic documentation post-surgery in the CON, LUC, KIN, and PPAR groups at 0, 1, 3, 5, and 7 days (A). Quantification of wound area on days 3 (B), 5 (C), and 7 (D). Statistical significance is indicated by *p < 0.05, **p < 0.01, ***p < 0.001, vs CON; #p < 0.05, ##p < 0.01, ###p < 0.001, vs LUC; +p < 0.05, ++p < 0.01, ++p < 0.001, vs KIN.
