Table 1.

The genes in the article and related diseases and treatments of them.

Gene	Related disease	Treatment
KCNA1	Epilepsy, Episodic Ataxia Type 1, SUDEP	carbamazepine, 4-aminopyridine, SUDEP prevention strategies
KCNA2	Epilepsy, Ataxia, Neurodevelopmental Disorders	4-Aminopyridine, ketogenic diet, gene therapy
KCNB1	Developmental and Epileptic Encephalopathy (DEE), Autism	Valproic acid, Angiotensin II, neuroprotective therapies
KCNC1	Epileptic Encephalopathy, Myoclonus Epilepsy, Ataxia	Small molecule Kv3 activators, pharmacological treatments
KCND2	Autism, Epilepsy, Cortical Malformations	Antagonizing miR-324-5p, Saikosaponin A
KCNQ2	Benign Familial Neonatal Epilepsy (BFNE), Encephalopathy	Carbamazepine, KCNQ openers like retigabine, cannabidiol, SCR2682
KCNQ3	Benign Familial Neonatal Epilepsy (BFNE), Developmental Delay	Similar treatments to KCNQ2, selective channel openers
KCNH1	Epileptic Encephalopathy, Autism	Benzodiazepine, phenytoin, valproate
KCNH5	Developmental and Epileptic Encephalopathy (DEE), Autism	Valproate, terbutaline