Table III.
Logistic regression model for polypharmacy
| Characteristics | Polypharmacy | |||||
|---|---|---|---|---|---|---|
| ≥ 5 drugs | ≥ 8 drugs | |||||
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Gender: | ||||||
| Women | – | – | – | 1.86 | 1.24–2.80 | 0.003 |
| Men | – | – | – | Base | – | – |
| Age | 1.05 | 1.02–1.08 | 0.002 | 1.02 | 1.00–1.04 | 0.109 |
| Number of chronic health problems: | 1.24 | 1.07–1.45 | 0.005 | 1.11 | 1.02–1.20 | 0.016 |
| A | 1.17 | 0.47–3.00 | 0.735 | – | – | – |
| D | 1.55 | 0.88–2.75 | 0.131 | 0.77 | 0.51–1.16 | 0.204 |
| F | – | – | – | 0.91 | 0.56–1.47 | 0.696 |
| H | 1.20 | 0.49–2.91 | 0.688 | – | – | – |
| K | 2.43 | 1.37–4.30 | 0.002 | 2.53 | 1.56–4.11 | < 0.001 |
| L | 0.66 | 0.39–1.13 | 0.130 | 0.99 | 0.67–1.48 | 0.974 |
| N | 0.62 | 0.31–1.27 | 0.195 | 1.13 | 0.68–1.87 | 0.644 |
| P | 0.98 | 0.55–1.75 | 0.953 | 0.96 | 0.64–1.46 | 0.851 |
| R | 1.19 | 0.61–2.33 | 0.619 | 1.06 | 0.68–1.67 | 0.788 |
| T | 1.49 | 0.86–2.61 | 0.159 | 1.32 | 0.87–2.01 | 0.192 |
| U | 0.67 | 0.35–1.26 | 0.214 | 1.03 | 0.64–1.65 | 0.909 |
| X | 1.24 | 0.45–3.38 | 0.678 | – | – | – |
| Y | 0-77 | 0.39–1.53 | 0.451 | 1.33 | 0.75–2.33 | 0.329 |
| Number of prescribers | 4.71 | 3.42–6.48 | < 0.001 | 2.32 | 1.97–2.73 | < 0.001 |
OR – odds ratio, A – general and unspecified, D – digestive, F – eye, H – ear, K – circulatory, L – musculoskeletal, N – neurological, P – psychological, R – respiratory, S – skin, T – endocrine, metabolic and nutritional, U – urology, X – female genital system and breast, Y – male genital system.