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. 2011 Nov 9;2011(11):CD004963. doi: 10.1002/14651858.CD004963.pub3

Taaffe 1999.

Methods Type of study: RCT
Participants Number of participants randomised: 46
Losses:7 (5 in exercise and 2 control)
N = 46 
 Age: 65 to 79 years 
 Sex: 29 males, 17 females
Health status as defined by authors: healthy 
 Residential status of participants: community dwellers
Setting: USA 
 Inclusion: BMI < 30 Kg/m2 
 Exclusion: musculoskeletal disorders inhibiting exercise, participation in weight training in past 12 months
Interventions EXERCISE GROUP (STRENGTH): high intensity progressive resistance training at 80% of 1 RM (repetition maximum) (repetition maximum) for upper and lower limbs. 
 CONTROL GROUP: usual activity 
 Duration and intensity: Ex1 = 1 day per week for 24 weeks, Ex2 = 2 days per week for 24 weeks, Ex3 = 3 days per week for 24 weeks 
 Supervisor: not stated 
 Supervision: group with direct supervision 
 Setting: gym
Outcomes backward tandem walk over 6 m
Compliance/adherence: similar across interventions
Adverse events: not reported
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information to permit judgement
Allocation concealment (selection bias) Unclear risk Insufficient information to permit judgement
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Insufficient reporting of attrition/exclusions to permit judgement
Selective reporting (reporting bias) Unclear risk Insufficient information to permit judgement
Other bias Low risk The study appears to be free of other sources of bias
Blinding (participant) High risk Not possible
Blinding (assessor) Unclear risk Insufficient information to permit judgement
Were the treatment and control group comparable at entry? Low risk No differences reported on baseline characteristics with a potential to influence the effect of the intervention
Was the surveillance active, and of clinically appropriate duration (i.e. at least 3 months post intervention)? High risk Only immediately post intervention data, no follow‐up data reported.