TABLE 2.
Amino acid sequences of HTLV-1 CA mutants
| Mutated site | Wild-type sequencea | Mutated sequences
|
|
|---|---|---|---|
| CAi | CAs | ||
| CA 1 | 51TAKDLQDL | 51TAKRSAGRSQDL | 51TAKRSQDL |
| C63 | 60QYLCSSL | 60QYLASSL | |
| CA 2 | 65SLVASLHH | 65SLVRSAGRSLHH | 65SLVRSLHH |
| CA 3 | 78LISEAETR | 78LISRSAGRSETR | 78LISRSETR |
| CA 4 | 92PLAGPLRV | 92PLADIAGDILRV | 92PLADILRV |
| CA 5 | 100QANNPQQQ | 100QANRSAGRSQQQ | 100QANRSQQQ |
| CA 6 | 116LWLAAFA | 116LWLPAFA | |
| CA 7 | 139GLEEPYH | 139GLEKPYH | |
| CA 9 | 169LRSLAYS | 169LRSSAYS | |
| CA 10 | 174YSNANKEC | 174YSNRSAGRSKEC | 174YSNRSKEC |
| CA 11 | 182QKLLQARG | 182QKLRSAGRSARG | 182QKLRSARG |
| CA 12 | 192NSPLGDM | 192NSPRGPRGDM | 192NSPRGDM |
a
The wt amino acids of the HTLV-1 CA mutated sites and their corresponding insertion (CAi) and/or substitution (CAs) mutations are underlined. Amino acid numbering starts at the first amino acid of the HTLV-1 CA protein.