. 2024 Aug 19;30(Suppl):S5–S105. doi: 10.3350/cmh.2024.0506

Table 14.

Serum markers for diagnosing liver steatosis in patients with NAFLD

Panel	Calculation Method	Cutoff value	AUC
FLI [268]	(e^{0.953 × loge(triglycerides [mg/dL]) + 0.139 x BMI [kg/m²]+ 0.718 × loge(GGT [IU/L]) + 0.053 × waist circumference [cm] - 15.745})/(1 + e^{0.953 × loge (triglyceride s[mg/dL]) + 0.139 × BMI [kg/m²] + 0.718 × loge(GGT[IU/L]) + 0.053 × waist circumference [cm] - 15.745})×100	≥60 (diagnosis), <30 (exclusion)	0.85
NLFS [269]	–2.89+1.18×metabolic syndrome (yes=1, no=0)+0.45×T2DM (yes=2, no=0)+0.15×(fasting insulin [μU/L])+0.04×AST [IU/L]+0.94×AST/ALT	>–0.64	0.86–0.87
HSI [270]	8×ALT/AST+BMI [kg/m²] (T2DM +2; female +2)	≥36 (diagnosis), <30 (exclusion)	0.81

NAFLD, nonalcoholic fatty liver disease; FLI, fatty liver index; NLFS, nonalcoholic fatty liver disease liver fat score; HSI, hepatic steatosis index; BMI, body mass index; GGT, gamma-glutamyl transferase; T2DM, type 2 diabetes mellitus; AST, aspartate aminotransferase; ALT, alanine transaminase; AUC, area under the curve.