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. 2024 Aug 19;30(Suppl):S5–S105. doi: 10.3350/cmh.2024.0506

Table 18.

Diagnostic performance of shear wave elastography for liver fibrosis in patients with ALD

Reference No. of patients Nation Test Significant fibrosis (≥F2)
Advanced fibrosis (≥F3)
Cirrhosis (F4)
No. of patients (%) AUC (95% CI) Cutoff value Sensitivity%/specificity% No. of patients (%) AUC (95% CI) Cutoff value Sensitivity%/specificity% No. of patients (%) AUC (95% CI) Cutoff value Sensitivity%/specificity%
Zhang et al. [305] (2015) 99 China pSWE 60 (60.6) 0.85 (0.77-0.92) 1.27 m/s 77.0/85.0 25 (25.2) 0.88 (0.79–0.96) 1.4 84.0/82.0 9 (9.1) 0.89 (0.82–0.96) 1.65 m/s 89.0/84.0
Kiani et al. [319] (2016) 82 France pSWE 34 (41.5) 0.87 1.63 m/s 82.4/83.3 17 (20.7) 0.86 1.84 82.4/78.5 13 (15.9) 0.89 1.94 m/s 92.3/81.6
Cho et al. [320] (2020) 251 Korea pSWE 204 (81.3) 0.93 (0.89–0.97) 1.46 m/s 84.8/89.4 175 (69.7) 0.90 (0.86–0.95) 1.47 90.9/76.3 144 (57.3) 0.91 (0.87–0.95) 1.66 m/s 97.2/74.8
Thiele et al. [312] (2016) 199 Denmark 2D-SWE 84* (42.2) 0.94 (0.91–0.97) 10.2 kPa 82.0/93.0 - - - - 36 (18.1) 0.95 (0.92–0.98) 16.4 kPa 94.0/91.0
Thiele et al. [303] (2018) 289 Denmark 2D-SWE 146 (50.5) 0.88 (0.84–0.92) - - 66 (23.0) 0.97 (0.94–0.99) 16.4 90.0/96.0 49 (17.0) 0.97 (0.94–0.99) - -

ALD, Alcohol-related liver disease; pSWE, point shear wave elastography; 2D-SWE, 2D shear wave elastography. AUC, area under the curve; CI, confidence interval; kPa, kilopascal.

*

Ishak ≥3.

Ishak ≥5.