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Synthesis of (A) IMTi-2 analogs, and (B) IMTi-3. Key: i) Pd(dba)3, XanthPhos, Cs2CO3, 1,4-Dioxane, microwave, 100°C, 2 h ii) Na(OAc)3BH, DCE, AcOH. iii) Boc2O, ACN. iv) TFA, TIPS, CH2Cl2, 0°C-RT, 2 h v) DIEA, THF, RT, 3 h vi) DIEA, THF, 90°C, 2 h vii) 4M HCl in dioxane, EtOAc, RT, 2 h.
