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MR analysis of the mediation role of immune cells in the relationship between gut microbiota and coagulation defects, purpura, and other hemorrhagic conditions.
| Exposure | Mediator | Outcome | Total Effect Beta | Mediation Beta | Proportion of Mediation Effect |
|---|---|---|---|---|---|
| Gut Microbiota ID | Immune Cell ID | ||||
| GCST90027751 | GCST90001810 | CPH | -0.216 | -0.016 | 7.26% |
| GCST90027684 | GCST90001842 | CPH | 0.303 | -0.009 | / |
| GCST90027745 | GCST90001842 | CPH | 0.303 | -0.009 | / |
| GCST90027845 | GCST90001420 | CPH | -0.134 | 0.008 | / |
