Table 1.
List of DAPs for rhesus macaques (aged vs. young). Accession number, protein name, gene name, p-value and log2 Fold Change are provided. Proteins are ordered by increasing p-value. Top 5 DAPs are highlighted in bold
| Accession Number | Protein name | Gene name | p-value | Log2 Aged Rhesus |
|---|---|---|---|---|
| F7EDT3 | Calpain 5 | CAPN5 | 0.00015 | 1.45 |
| F6TSU2 | Protein-tyrosine-phosphatase receptor J | PTPRJ | 0.0011 | -0.771 |
| F7H1V9 | Pentraxin | APCS | 0.0012 | 1.14 |
| F6UQB6 | Heme-binding protein 1 | HEBP1 | 0.0015 | 1.46 |
| F6V089 | t-SNARE coiled-coil homology domain-containing protein | PPP1R8 | 0.0021 | -0.644 |
| A0A1D5Q9N1 | Radixin | RDX | 0.0031 | -0.875 |
| F7ESZ3 | Biglycan | BGN | 0.0032 | 3.03 |
| A0A1D5R6M8 | Immunoglobulin heavy constant mu | IGHM | 0.0045 | 1.06 |
| A0A5F7ZIS1 | RALY heterogeneous nuclear ribonucleoprotein | RALY | 0.0052 | -0.533 |
| F6YXJ2 | Deoxyribonuclease II | DNASE2 | 0.0054 | -0.936 |
| F6R2V4 | BAG cochaperone 3 | BAG3 | 0.0057 | -0.799 |
| F7C9U4 | CD93 molecule | CD93 | 0.0059 | -0.669 |
| H9FSW2 | Argonaute RISC component 1 | AGO1 | 0.0066 | -1.38 |
| F6RJC0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase | PLCB3 | 0.007 | 2.33 |
| F6SFP9 | D-aminoacyl-tRNA deacylase | DTD1 | 0.0079 | -1.1 |
| A0A1D5QRS2 | Histone H2A | H2AC12 | 0.0082 | 2.81 |
| F6ZAW8 | Hippocalcin like 1 | HPCAL1 | 0.0085 | -0.755 |
| G7MHG1 | Complement C1q subcomponent subunit B | C1QB | 0.0089 | 2.05 |
| F7GPV6 | Multifunctional protein ADE2 | PAICS | 0.0092 | -1.34 |
| A0A5F7ZHW5 | Lectin, mannose binding 2 | LMAN2 | 0.0095 | 0.64 |
| F7FMM5 | TROVE domain-containing protein | RO60 | 0.01 | -0.605 |
| A0A5F7ZQM9 | Proteasome 20S subunit beta 8 | PSMB8 | 0.012 | -0.726 |
| A0A1D5Q716 | Uncharacterized protein | MCAM | 0.012 | -0.519 |
| A0A5F7Z998 | Vitronectin | VTN | 0.012 | 0.589 |
| A0A1D5Q3K1 | NAD(P)H-hydrate epimerase | NAXE | 0.013 | -1.02 |
| F7EHH7 | Protein-tyrosine-phosphatase | PTPRG | 0.013 | -0.71 |
| A0A5F8A5N3 | Uncharacterized protein | NAPG | 0.013 | 0.893 |
| F7E8L2 | Phosphoenolpyruvate carboxykinase (GTP) | PCK2 | 0.013 | 1.21 |
| P00002 | Cytochrome c | CYCS | 0.014 | -0.56 |
| F7HSJ5 | Histone H2A | H2AC21 | 0.014 | 3.15 |
| A0A5F7ZEM7 | Early endosome antigen 1 | EEA1 | 0.015 | -1.11 |
| A0A1D5QTI7 | 60S ribosomal protein L17 | RPL17 | 0.015 | -0.605 |
| F7DJM1 | SEC22 vesicle-trafficking protein homolog B | SEC22B | 0.015 | 0.62 |
| F6UZQ6 | Reticulon | RTN4 | 0.015 | 0.637 |
| F7H9U1 | Latent transforming growth factor beta binding protein 4 | LTBP4 | 0.017 | -1.24 |
| G7N7C5 | Citrate synthase | CS | 0.018 | -0.523 |
| A0A1D5Q3X0 | Cysteinyl-tRNA synthetase | CARS1 | 0.018 | 0.642 |
| A0A1D5R2U5 | IK cytokine | IK | 0.019 | -1.2 |
| A0A1D5RGB7 | EWS RNA binding protein 1 | EWSR1 | 0.02 | -1.1 |
| F6YK65 | C3/C5 convertase | CFB | 0.02 | 0.827 |
| F6QAX2 | Tubulin beta chain | TUBB3 | 0.02 | 1.58 |
| F6W1K5 | UBX domain protein 1 | UBXN1 | 0.021 | -1.2 |
| A0A5F7ZJ61 | Transforming acidic coiled coil containing protein 2 | TACC2 | 0.021 | -0.671 |
| A0A5F7ZWV4 | Secernin 1 | SCRN1 | 0.021 | 0.576 |
| A0A1D5RGN2 | Cell adhesion molecule 1 | CADM1 | 0.022 | -1.66 |
| A0A1D5Q4R1 | Protein-tyrosine-phosphatase | PTPRM | 0.022 | -1.22 |
| A0A1D5R9J9 | Nucleoside diphosphate kinase | NME3 | 0.022 | -0.721 |
| F7CA88 | Ribonuclease inhibitor | LOC720791 | 0.022 | -0.558 |
| A0A5F7Z9N3 | 60S ribosomal protein L4 | RPL4 | 0.022 | 0.587 |
| F7H400 | Kinectin 1 | KTN1 | 0.023 | -0.898 |
| A0A5F8APU1 | U6 snRNA-associated Sm-like protein LSm4 | LSM4 | 0.023 | -0.697 |
| A0A5F7ZVB9 | Inter-alpha-trypsin inhibitor heavy chain 2 | ITIH2 | 0.023 | 1.28 |
| F6UZ20 | Fibrinogen gamma chain | FGG | 0.023 | 1.57 |
| A0A1D5R0R7 | Histone H2B | H2BC5 | 0.023 | 3.33 |
| F7HAP4 | Histone H2A | H2AC6 | 0.023 | 3.94 |
| F7CDG7 | U1 small nuclear ribonucleoprotein 70 kDa | SNRNP70 | 0.024 | -1.05 |
| A0A1D5RJP5 | Arylsulfatase B | ARSB | 0.024 | -0.66 |
| F6TCB7 | Bis(5'-adenosyl)-triphosphatase | FHIT | 0.025 | -1.33 |
| A0A5F7ZHK9 | H15 domain-containing protein | H1-2 | 0.025 | 1.01 |
| F6QXG0 | Angiopoietin-2 | ANGPT2 | 0.025 | 1.49 |
| A0A5F7ZA28 | Uncharacterized protein | FUBP3 | 0.026 | -1.1 |
| A0A5F7ZC04 | Transcription elongation factor SPT5 | SUPT5H | 0.026 | -0.651 |
| A0A1D5R7P5 | Inositol-1-monophosphatase | IMPA1 | 0.027 | -1.34 |
| A0A1D5QIK3 | SAFB like transcription modulator | SLTM | 0.027 | -0.724 |
| A0A5F8ANH4 | Coagulation factor II | F2 | 0.027 | 1.11 |
| A0A1D5QZ18 | Complement component 8 subunit beta | C8B | 0.027 | 1.26 |
| A0A5F8AKB8 | Histone H2B | H2BC17 | 0.027 | 3.3 |
| A0A1D5R536 | Kinectin 1 | KTN1 | 0.028 | -0.864 |
| F6UZ60 | Fibrinogen alpha chain | FGA | 0.028 | 1.12 |
| F7HAB9 | Golgi associated, gamma adaptin ear containing, ARF binding protein 1 | GGA1 | 0.029 | -1.37 |
| F6WIQ0 | Uncharacterized protein | SET | 0.029 | -1.32 |
| A0A5F7ZB67 | Pyruvate kinase | PKLR | 0.029 | 0.721 |
| A0A1D5R9K8 | Microfibril associated protein 4 | MFAP4 | 0.029 | 0.828 |
| A0A1D5QPA5 | KH-type splicing regulatory protein | KHSRP | 0.03 | -0.814 |
| I0FHZ5 | Phosphoinositide phospholipase C | PLCD1 | 0.03 | 0.748 |
| A0A5F7ZAZ2 | C1q domain-containing protein | C1QC | 0.03 | 1.37 |
| A0A5F7ZNS5 | Uncharacterized protein | ACOT2 | 0.03 | 1.85 |
| A0A1D5QVX8 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase | NAXD | 0.031 | -1.14 |
| A0A5F8A3T7 | Ig-like domain-containing protein | 0.031 | 0.79 | |
| F7AL41 | Formin-binding protein 1-like | FNBP1L | 0.032 | -0.837 |
| F7GRA6 | Complement C8 gamma chain | C8G | 0.032 | 0.7 |
| A0A1D5RJK6 | Uncharacterized protein | FUBP1 | 0.033 | -1.07 |
| H9END9 | Tropomyosin alpha-4 chain isoform 2 | TPM4 | 0.033 | -0.624 |
| A0A5F7ZEZ9 | Fibrinogen beta chain | FGB | 0.034 | 1.72 |
| A0A5F7ZFX7 | Fructose-bisphosphatase | FBP2 | 0.035 | -1.25 |
| A0A5F7ZJW9 | Uncharacterized protein | MANF | 0.035 | -0.838 |
| F6YBP7 | Adipsin | CFD | 0.035 | 1.03 |
| H9Z3B8 | Copper transport protein ATOX1 | ATOX1 | 0.036 | -0.942 |
| A0A1D5R0N5 | Uncharacterized protein | MYL6 | 0.036 | 0.572 |
| A0A1D5Q833 | PTPRF interacting protein alpha 1 | PPFIA1 | 0.037 | -1.02 |
| A0A1D5QJR4 | Host cell factor C1 | HCFC1 | 0.039 | -1.04 |
| F7GXX7 | Small ubiquitin-related modifier | SUMO1P1 | 0.039 | -0.968 |
| A0A1D5QFS4 | Scaffold attachment factor B | SAFB | 0.039 | -0.889 |
| F7APH2 | Heterogeneous nuclear ribonucleoprotein D0 isoform c | HNRNPD | 0.039 | -0.556 |
| F6T0W5 | Tetranectin | CLEC3B | 0.04 | 0.803 |
| F6QQP0 | Uncharacterized protein | 0.041 | 0.737 | |
| A0A1D5QMN6 | Serpin family B member 6 | SERPINB6 | 0.042 | -0.577 |
| F6SJD2 | CXXC motif containing zinc binding protein | CZIB | 0.042 | 0.678 |
| A0A5F7ZI29 | Uncharacterized protein | JCHAIN | 0.042 | 0.731 |
| F6TQ14 | Carbonic anhydrase | CA2 | 0.042 | 0.92 |
| F7F874 | Thiamine pyrophosphokinase | TPK1 | 0.043 | -1.18 |
| F7FF62 | Proteasome activator complex subunit 1 isoform 1 | PSME1 | 0.043 | -0.76 |
| A0A5F7ZKJ3 | Pyruvate dehydrogenase phosphatase regulatory subunit | PDPR | 0.043 | 1.06 |
| F7HNR1 | Anterior gradient 2, protein disulphide isomerase family member | AGR2 | 0.043 | 2.74 |
| H9FXA8 | Proteasome subunit alpha type | PSMA7 | 0.044 | -0.848 |
| A0A1D5QYN2 | Glutathione reductase | GSR | 0.044 | -0.611 |
| I0FNJ1 | Epididymal secretory protein E1 | NPC2 | 0.045 | -0.777 |
| F7FLX2 | GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase | GFUS | 0.045 | 0.503 |
| F7F6K7 | Junctional cadherin 5 associated | JCAD | 0.046 | -2.05 |
| A0A5F8ATC0 | Eukaryotic translation initiation factor 2 subunit beta | EIF2S2 | 0.046 | -0.827 |
| A0A1D5QSC4 | Epidermal growth factor receptor pathway substrate 15 | EPS15 | 0.046 | -0.703 |
| A0A5F8A837 | Uncharacterized protein | SUGT1 | 0.046 | -0.563 |
| F7F2A5 | Metavinculin | VCL | 0.046 | -0.5 |
| F7HER2 | Actinin alpha 3 | ACTN3 | 0.048 | -0.771 |
| G7MLE5 | Phosphoglycerate mutase | PGAM2 | 0.048 | -0.542 |
| F7E3N5 | Phosphatase domain containing paladin 1 | PALD1 | 0.048 | -0.524 |
| A0A5F8ATN0 | Histone H2A | H2AZ2 | 0.048 | 2.66 |
| A0A5F8AJ37 | RAB8B, member RAS oncogene family | RAB8B | 0.049 | -0.55 |
| F7H4P3 | Proteasome subunit beta | PSMB4 | 0.05 | -0.804 |
| A0A5F7ZMU2 | Uncharacterized protein | CFHR5 | 0.05 | 0.766 |