Table 4.
Results of mixed model 2 during standardized supine-stand tests in the subgroup of participants with OH with participants as random effects and group (“symptomatic” (modeled as 1) or “asymptomatic” (modeled as 0)) and condition (“laboratory” (modeled as 0) or “at home” (modeled as 1)) as fixed effects on long- or short-channel oxygenation (O2Hb) parameters (maximum drop amplitude, early recovery (30–40 s after postural change), 1-min recovery (50–60 s after postural change), and late recovery (60–170 s after postural change)). n is the total number of supine-stand transitions (number of subjects of whom these supine-stand transitions are included)
O2Hb long | Fixed-effects group | Fixed-effects condition | Random effects | |||
n = 69 (10) | Estimate (95% CI) | p-value | Estimate (95% CI) | p-value | Variance | ICC |
Maximum drop | − 0.80 (− 1.57 to − 0.03) | 0.041* | 0.33 (− 0.35–1.01) | 0.334 | 0.60 | 0.32 |
Early recovery | − 0.38 (− 1.17–0.41) | 0.338 | 0.36 (− 0.36–1.08) | 0.324 | 0.33 | 0.18 |
1-min recovery | − 0.19 (− 1.12–0.74) | 0.683 | 0.16 (− 0.69–1.01) | 0.708 | 0.39 | 0.16 |
Late recovery | − 0.66 (− 1.51–0.18) | 0.121 | 0.07 (− 0.71–0.84) | 0.861 | 0.36 | 0.17 |
O2Hb short n = 65 (10) |
||||||
Maximum drop | − 1.75 (− 3.40 to − 0.09) | 0.039* | − 0.94 (− 2.40–0.51) | 0.198 | 2.04 | 0.26 |
Early recovery | − 1.51 (− 3.22–0.20) | 0.083 | − 0.69 (− 2.20–0.82) | 0.363 | 2.01 | 0.25 |
1-min recovery | − 1.19 (− 3.40–1.02) | 0.287 | − 1.06 (− 3.02–0.90) | 0.282 | 3.03 | 0.23 |
Late recovery | − 1.45 (− 3.68–0.76) | 0.193 | − 0.41 (− 2.49–1.67) | 0.691 | 0.90 | 0.07 |