A compound-target pairs dataset: differences between drugs, clinical candidates and other bioactive compounds

. 2024 Oct 21;11:1160. doi: 10.1038/s41597-024-03582-9

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Fig. 3 — The effects of including literature sources and BindingDB data in the calculation of the dataset. The plots are based on ChEMBL 32 and are limited to the time between 2000 and 2023. (a) The number of compounds deposited into ChEMBL from BindingDB and from literature sources by year. (b) The percentage of compounds in the dataset first published in a given year when all sources are included. (c) The percentage of compounds per one of the ten most frequent target classes first published in a given year when all sources are included. (d) The percentage of compounds in the dataset first published in a given year when only literature sources are included. (e) The percentage of compounds per one of the ten most frequent target classes first published in a given year when only literature sources are included.

Fig. 3.