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Risk stratification framework. Definite risk factors include immunocompromise, obesity, diabetes (type 1/2), prematurity, chronic cardiac, neurologic, or pulmonary disease (excluding asthma). Probable risk factors include sickle cell disease, mild/moderate immunocompromise, neuro-disabilities, chronic kidney, gastrointestinal or liver disease. Prior immunity is defined as up-to-date immunization or recent infection within the previous 4 months.
