Table 1. Positive clones from the screen.
Activators | No. of clones | cDNA insert |
---|---|---|
Kinases | ||
PKD2 | 1 | 118 amino acid to the end |
PKCδ | 1 | 237 amino acid to the end |
Mark2 | 3 | Full length |
Receptors | ||
Endothelin receptor type A | 5 | All full length |
EDG3 | 1 | Full length |
EDG4 | 3 | All full length |
EDG7 | 1 | Full length |
5HTR2B | 2 | 89 amino acid to the end and full length |
ErbB-2 | 1 | 487 amino acid to the end |
Regulators of Rho signaling | ||
RhoA | 1 | Full length |
Rho C | 1 | Full length |
Rho GEF1 | 1 | 383 amino acid to the end |
Rho GEF5 | 1 | 1002 amino acid to the end |
Transcriptional regulators | ||
PIAS 4 | 1 | Full length |
COUP-TFII | 2 | Both full length |
Ebfaz | 1 | 6 amino acid to the end |
Others | ||
Cyclin A2 | 1 | Full length |
Chloride channel intracellular protein 1 | 1 | Full length |
PNAS-2 | 1 | Full length |
SENP2 | 3 | 349 amino acid to the end and full length |
Putative MAPK/NFκB activating protein | 1 | Full length |
Novel | 3 | Unknown |
Proteins encoded by cDNA clones isolated in the expression screen described in Fig. 1A are shown. The number of clones of each type that were isolated and the amino acids encoded by the clones are shown. PKD, protein kinase D; Mark2, microtubule-associating regulatory kinase 2; EDG, endothelial differentiation gene; GEF, guanine nucleotide exchange factor; PIAS, protein inhibitor of activated STAT; Ebfaz, early B cell factor-associated zinc finger gene; SENP2, small ubiquitin-related modifier 1/sentrin/SMT3-specific protease 2.