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. 2024 Sep 26;16(9):6320–6338. doi: 10.21037/jtd-24-450

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Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Hermansky-Pudlak syndrome. (A,B) HRCT shows subpleural reticulation (mainly in left lung), with traction bronchiectasis and honeycombing changes. (C,D) The patient presented acute exacerbation of pulmonary fibrosis. HRCT revealed patchy ground-glass infiltrates superimposed on fibrotic changes. (E) Left lower lobe lung biopsy: unspecific changes, normal areas alternating with others with inflammation and lax fibrosis with collagenized fibrosis. Hematoxylin-eosin staining ×2. Courtesy of Dr. J. L. Mate. HRCT, high-resolution computed tomography.