Table 2.

Interrupted time series analysis for effect of PCV10 on the incidence of pneumococcal meningitis among children < 5 in PBM sentinel surveillance host districts, Uganda, from 2003–2022

District	Pre-PCV10 (2003–2013)		Post-PCV10 (2014–2022)
	Trend (slope change)		Immediate (level change)		Trend (slope change)
	Estimated change (95%CI)	P-value	Estimated change (95%CI)	P-value	Estimated change (95%CI)	P-value
Kampala City	0.11206 (-2.80445,3.02862)	0.94	-1.85145 (-1.92094,-1.782)	< 0.001	-0.99997(-1.00002,-0.99997)	< 0.001
Gulu District	0.99995 (0.99985,1.00006)	< 0.001	-0.19783 (-1.31913,0.92346)	0.729	-0.99992 (-1.00115,-0.99869)	< 0.001
Overall	1.0 (0.99999,1.00001)	< 0.001	0.00024(-0.00029,-0.00033)	0.881	-1.00006 (-1.00033,-0.99979)	< 0.001