Table 1.
Patient demographics and clinical characteristics.
| All patients (N = 1,711) | Patients with HGSOC (n = 867) | |
|---|---|---|
| Demographic characteristics | ||
| Mean age at first diagnosis (SD), years | 65.9 ± 13.4 | 68.6 ± 10.8 |
| Stage | ||
| I | 381 (22.3) | 92 (10.6) |
| II | 89 (5.2) | 45 (5.2) |
| III | 575 (33.6) | 442 (51.0) |
| IV | 291 (17.0) | 203 (23.4) |
| BMI, n (%) | ||
| Underweight: < 18.5 kg/m2 | 38 (2.2) | 18 (2.1) |
| Normal weight: 18.5–24.9 kg/m2 | 617 (36.1) | 327 (37.7) |
| Overweight: 25–29.9 kg/m2 | 510 (29.8) | 285 (32.9) |
| Obese: > 30.0 kg/m2 | 361 (21.0) | 169 (19.5) |
| Unknown | 185 (10.8) | 68 (7.8) |
| Geographic region, n (%) | 1,042 (60.9) | 522 (60.2) |
| Helsinki | 363 (21.2) | 220 (25.4) |
| Tampere | 306 (17.9) | 125 (14.4) |
| Turku | ||
| Clinical characteristics | ||
| Location at initial diagnosis, n (%) | ||
| Ovaries | 1,281 (74.9) | 586 (67.6) |
| Fallopian tubes | 107 (6.3) | 95 (11.0) |
| Adnexa, others | 84 (4.9) | 67 (7.7) |
| Peritoneum and retroperitoneum | 239 (14.0) | 119 (13.7) |
| Histological grading, n (%) | ||
| Serous, high-grade | 867 (50.7) | 867 (100) |
| Serous | 212 (12.4) | – |
| Serous, low-grade | 58 (3.4) | – |
| Mucinous | 107 (6.3) | – |
| Endometrioid | 101 (5.9) | – |
| Clear cell | 73 (4.3) | – |
| Mesenchyme | 66 (3.9) | – |
| Other | 227 (13.3) | – |
| BRCA mutation status, n (%) | ||
| BRCAmut | 30 (1.8) | 28 (3.2) |
| BRCAwt | 282 (16.5) | 212 (24.5) |
| Unknown | 1,399 (81.8) | 627 (72.3) |
| Residual tumoura, n (%) | ||
| R0 | 471 (39.5) | 270 (31.1) |
| R1 | 174 (14.6) | 141 (16.3) |
| R2 | 133 (11.2) | 107 (12.3) |
| Unknown | 413 (34.7) | 349 (40.3) |
a
The residual tumour status is presented only for patients who underwent surgery.
BMI: body mass index; HGSOC: high-grade serous ovarian cancer; OC: ovarian cancer; SD: standard deviation.