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Replication capacities of wild-type BH10 and mutated viruses containing substitutions of T12 in p2. Mutations are represented by single-letter abbreviations of amino acids. UAG is a stop codon that was inserted at position 12 in p2. (A) Growth curves of wild-type and mutated viruses after infection of MT-2 cells. (B) RT activity in culture supernatants at day 7 after infection. Mock represents a negative control performed with heat-inactivated wild-type virus.
