TABLE 2.
Summary of the various pharmacological effects of ISL metabolites.
| Compound | Structural formula | Pharmacological effects | References |
|---|---|---|---|
| Liquiitigenin |
|
Neuroprotective activities Anti-nociception activities Anti-bacterial activities Anti-asthmatic effects Anti-diabetic activities Hepatoprotective activities Anti-cancer activities |
Chokchaisiri et al. (2009), Jayaprakasam et al. (2009), Kim et al. (2009), Straub et al. (2013), Yang et al. (2013), Paterni et al. (2015), Bae et al. (2018) |
| Naringenin chalcone |
|
Anti-allergic skin disorders Anti-allergic asthma |
Yamamoto et al. (2004), Iwamura et al. (2010), Escribano-Ferrer et al. (2019) |
| Sulfuretin |
|
Enhancement of bone growth Anti-depressive effects Hepatoprotective activities Alleviation of atopic dermatitis Prevention of obesity |
Jiang and Sun (2018), Kim et al. (2019), Lu et al. (2019), Sun et al. (2022), Chang et al. (2023) |
| Butein |
|
Anti-cancer activities Treatment of bone cancer pain Alleviation of atherosclerosis Treatment of cardiac diseases |
Tungalag et al. (2022), Liu et al. (2023), Rehman et al. (2023), Lu et al. (2024) |
| Davidigenin |
|
Anti-cancer activities | Liu et al. (2002), Keranmu et al. (2022) |