FIG. 5.

Comparative growth curves of Ad5/FibWT virus (solid line) and Ad5/FibR7-RGD recombinant (dotted line). HEK-293 cells were infected with the same input multiplicity (10 PFU/cell) for 1 h at 37°C, then cells were harvested and lysed at different times postinfection, as indicated. Infectious titer of each sample was determined by fluorescent plaque assay in 293 cell monolayers. Data shown are the average of three separate experiments ± SD.