Table 5.
Factors predictive of supportive care needs in young adult cancer survivors at 3 years post-diagnosis in multivariable logistic regression models
| Factors | Global QoL OR (CI) |
Physical Function OR (CI) |
Role Function OR (CI) |
Emotional Function OR (CI) |
Social Function OR (CI) |
Fatigue OR (CI) |
Nausea/Vomiting OR (CI) |
Pain OR (CI) |
Sleep Disturbances OR (CI) |
|---|---|---|---|---|---|---|---|---|---|
| Age | |||||||||
| 0.99 (0.95–1.03) | 0.99 (0.96–1.03) | 1.00 (0.96–1.05) | 1.00 (0.96–1.04) | 1.02 (0.98–1.07) | 1.02 (0.97–1.06) | 0.96 (0.92–1.01) | 1.02 (0.98–1.06) | 1.03 (0.99–1.08) | |
| Cancer type | |||||||||
| Lymphoma (ref) | |||||||||
| Breast | 1.26 (0.67–2.36) | 0.94 (0.50–1.78) | 1.39 (0.73–2.64) | 1.20 (0.61–2.34) | 1.07 (0.56–2.02) | 0.51 (0.25–1.03) | 1.16 (0.62–2.17) | 2.07 (1.12–3.85)a | 0.77 (0.41–1.47) |
| Cervical | 0.79 (0.40–1.55) | 0.72 (0.37–1.40) | 0.97 (0.48–1.95) | 1.26 (0.62–2.58) | 0.58 (0.29–1.16) | 0.45 (0.21–0.94)a | 0.64 (0.32–1.28) | 1.84 (0.96–3.56) | 0.60 (0.30–1.19) |
| Ovarian | 1.16 (0.36–3.67) | 0.56 (0.18–1.77) | 0.43 (0.13–1.46) | 1.36 (0.37–5.00) | 0.15 (0.04–0.58)b | 0.67 (0.18–2.47) | 1.47 (0.51–4.27) | 1.79 (0.59–5.46) | 0.46 (0.15–1.42) |
| Brain tumor | 1.01 (0.49–2.08) | 0.85 (0.41–1.76) | 1.60 (0.78–3.30) | 1.19 (0.56–2.54) | 1.07 (0.52–2.21) | 0.46 (0.21–1.01) | 0.65 (0.31–1.36) | 1.15 (0.57–2.34) | 0.94 (0.45–1.95) |
| Testicular | 1.10 (0.57–2.12) | 0.49 (0.25–0.95)a | 0.48 (0.23–1.01) | 0.61 (0.30–1.21) | 0.41 (0.20–0.82)a | 0.35 (0.17–0.73)b | 0.39 (0.19–0.81)a | 1.16 (0.61–2.21) | 0.84 (0.43–1.64) |
| Relationship status | |||||||||
| Partner (ref) | |||||||||
| No partner | 0.75 (0.45–1.27) | 0.73 (0.44–1.22) | 0.81 (0.47–1.40) | 0.74 (0.43–1.28) | 0.81 (0.47–1.39) | 0.62 (0.36–1.06) | 0.77 (0.45–1.32) | 1.41 (0.84–2.36) | 1.08 (0.63–1.83) |
| Self-rated economy | |||||||||
| Good (ref) | |||||||||
| Poor | 2.39 (1.34–4.27)b | 2.23 (1.28–3.89)b | 3.02 (1.78–5.13)c | 2.93 (1.45–5.93)b | 2.45 (1.40–4.28)b | 2.59 (1.40–4.81)b | 2.81 (1.72–4.59)c | 1.78 (1.04–3.06)a | 1.46 (0.84–2.52) |
| Have child(ren) | |||||||||
| No (ref) | |||||||||
| Yes | 1.10 (0.70–1.73) | 0.67 (0.43–1.05) | 0.98 (0.61–1.57) | 0.49 (0.30–0.79)b | 1.01 (0.64–1.60) | 0.92 (0.57–1.49) | 1.20 (0.76–1.92) | 0.60 (0.39–0.93)a | 0.74 (0.47–1.16) |
| Country of birth | |||||||||
| Sweden (ref) | |||||||||
| Other | 1.10 (0.65–1.87) | 1.46 (0.86–2.48) | 1.02 (0.59–1.75) | 1.16 (0.66–2.02) | 0.98 (0.57–1.69) | 0.93 (0.53–1.62) | 1.07 (0.62–1.83) | 1.57 (0.92–2.68) | 0.88 (0.52–1.49) |
| Education | |||||||||
| Other (ref) | |||||||||
| Universityd | 0.88 (0.61–1.26) | 0.72 (0.50–1.02) | 0.85 (0.59–1.24) | 0.60 (0.40–0.88)b | 0.69 (0.47–1.00)a | 0.79 (0.53–1.16) | 0.93 (0.64–1.36) | 0.78 (0.54–1.11) | 0.95 (0.67–1.36) |
| Chronic condition(s) | |||||||||
| None (ref) | |||||||||
| One or several | 3.17 (1.78–5.65)c | 1.76 (1.04–3.00)a | 2.32 (1.38–3.90)b | 2.09 (1.16–3.77)a | 2.04 (1.18–3.52)a | 1.62 (0.88–2.98) | 1.40 (0.84–2.32) | 1.91 (1.11–3.29)a | 1.04 (0.62–1.76) |
| Score at 1.5 years | |||||||||
| 0.94 (0.93–0.96)c | 0.93 (0.91–0.95)c | 0.97 (0.97–0.98)c | 0.96 (0.95–0.97)c | 0.96 (0.96–0.97)c | 1.05 (1.04–1.07)c | 1.03 (1.01–1.04)c | 1.04 (1.03–1.05)c | 1.04 (1.03–1.04)c | |
Supportive care needs based on EORTC QLQ-C30 cut-off scores Lidington et al. [21]. Age and corresponding EORTC scale scores at 1.5 years post-diagnosis as continuous variables. Significant values (P < 0.05) in bold. Missing values = 35–39
CI confidence interval, OR odds ratio, QoL quality of life
aP < 0.05
bP < 0.01
cP < 0.001
dOngoing or completed university or college
Bold values indicate statistical significance