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. 2024 Oct 22;14:24804. doi: 10.1038/s41598-024-74604-0

Table 3.

EC100, IC50 (µg/mL), and SI values of the modified GO-SA-LPO composite against Wi-38, Caco-2, and HCT-166 cell lines after treatment for 48 h compared with free LPO and GO-SA composite.

Cell lines LPO GO-SA composite GO-SA-LPO composite
Wi-38 EC100 53 ± 2.44 18 ± 1.17 46 ± 2.65
IC50 1350 ± 52.13 792.4 ± 57.54 1097 ± 59.68
Caco-2 EC100 59 ± 3.58 15 ± 1.39 23 ± 1.74
IC50 1488 ± 24.01 606 ± 10.74 296.8 ± 4.24
SI 0.91 ± 0.04 1.31 ± 0.09 3.69 ± 0.21
HCT166 EC100 48 ± 3.07 16 ± 1.23 21 ± 1.93
IC50 1116 ± 33.62 620.3 ± 7.33 262.7 ± 5.42
SI 1.21 ± 0.05 1.28 ± 0.09 4.18 ± 0.23

All data were expressed as mean ± SEM.