Table 3.
EC100, IC50 (µg/mL), and SI values of the modified GO-SA-LPO composite against Wi-38, Caco-2, and HCT-166 cell lines after treatment for 48 h compared with free LPO and GO-SA composite.
Cell lines | LPO | GO-SA composite | GO-SA-LPO composite | |
---|---|---|---|---|
Wi-38 | EC100 | 53 ± 2.44 | 18 ± 1.17 | 46 ± 2.65 |
IC50 | 1350 ± 52.13 | 792.4 ± 57.54 | 1097 ± 59.68 | |
Caco-2 | EC100 | 59 ± 3.58 | 15 ± 1.39 | 23 ± 1.74 |
IC50 | 1488 ± 24.01 | 606 ± 10.74 | 296.8 ± 4.24 | |
SI | 0.91 ± 0.04 | 1.31 ± 0.09 | 3.69 ± 0.21 | |
HCT166 | EC100 | 48 ± 3.07 | 16 ± 1.23 | 21 ± 1.93 |
IC50 | 1116 ± 33.62 | 620.3 ± 7.33 | 262.7 ± 5.42 | |
SI | 1.21 ± 0.05 | 1.28 ± 0.09 | 4.18 ± 0.23 |
All data were expressed as mean ± SEM.