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. 2024 Oct 29;84(18):1704–1717. doi: 10.1016/j.jacc.2024.08.052

Table 1.

Causes of Hospitalizations

Usual Care (n = 568) Ferric Derisomaltose (n = 569)
Deaths after randomization without preceding hospitalization 27 Deaths 21 Deaths
All Hospitalizations Main Cause
Main or Contributory
Main Cause
Main or Contributory
Events Patients Events Patients Events Patients Events Patients
All causes 1,086 370 (65) a a 904 351 (62) a a
CV 589 (54) 273 (48) a a 491 (54) 254 (45) a a
 Heart failure 286 152 345 179 222 130 269 152
 VT/VF 47 29 a a 26 22 a a
 AF/SVT 15 14 68b 53b 20 19 57b 43b
 ACS/MI 38 25 46 33 23 18 30 23
 Stroke 10 10 12 12 24 21 29 24
 AKI 28 24 193 144 21 19 165 114
 Hemorrhage 34 26 68 53 48 39 82 62
 Complications of CV therapy 42 37 205 147 36 35 202 142
 PTE 3 3 3 3 2 2 2 2
 Other 86 69 a a 69 63 a a
Non-CV 497 (46) 249 (44) a a 413 (46) 214 (38) a a
 Cancer 18 14 37 21 15 14 47 30
 Respiratory 45 31 196 124 29 21 137 93
 Infection 213 140 420 221 175 111 345 189
 Respiratory and infectionc a a 174 115 NA NA 130 88
 Renal 17 16 88 67 21 19 78 61
 Trauma and non-CV procedures 63 54 95 73 48 42 92 76
 Other 141 96 a a 125 94 a a

Values are n or n (%).

ACS = acute coronary syndrome; AF = atrial fibrillation; AKI = acute kidney injury (see text for explanation of cardiorenal); CV = cardiovascular; MI = myocardial infarction; PTE = pulmonary thromboembolism; SVT = supraventricular tachycardia; VF = ventricular fibrillation; VT = ventricular tachycardia.

a

Not appropriate or not calculated.

b

Arrhythmias complicating other hospitalizations were not further adjudicated as SVT or VT but were considered to be predominantly SVT.

c

Respiratory and infection includes patients with a respiratory admission with infection as contributory or admission for infection with respiratory disease as contributory. This includes patients in the 2 previous rows who had both as either main or contributory causes.