Table 2.

Main and Contributory Causes of Hospitalizations Associated With Worsening Heart Failure

	Usual Care			Ferric Derisomaltose
	HF Main Cause	HF Contributory	HF late Complicationa	HF Main Cause	HF Contributory	HF late Complicationa
Main cause	CV: 286	CV: 34 Non-CV: 31	CV: 29b Non-CV: 40	CV: 222	CV: 35 Non-CV: 17	CV: 32b Non-CV: 34
Cause for Admission	Contributory Cause	Main Cause When Not HF	Main Cause	Contributory Cause	Main Cause When Not HF	Main Cause
CV
HF	NA	NA	60c	NA	NA	63c
VT/VF	d	9	2	d	6	3
AF/SVT	29	3	3	16	3	3
ACS/MI	3	2	6	1	3	4
Stroke	1	0	0	0	1	1
AKI	89	6	1	66	7	4
Hemorrhage	12	1	4	10	3	7
Complications of CV therapy	23	1	5	25	3	3
PTE	0	1	1	0	0	0
Other CV	e	6	7	e	4	7
Non-CV
Cancer	2	1	0	3	0	1
Respiratory	40	3	3	32	2	3
Infection	78	19	25	60	8	19
Renal	5	0	0	0	1	1
Trauma	0	2	4	5	1	6
Other non-CV	e	6	8	e	5	4

Values are n.

NA = not applicable; other abbreviations as in Table 1.

^aHeart failure occurring as a late complication during an admission, including in-hospital worsening of heart failure admissions.

^bWhere heart failure was considered the main or contributory cause for admission, late exacerbations are not included in this figure, to avoid double-counting.

^cExacerbation of heart failure as a late complication of hospitalizations with heart failure as a main or contributory cause.

^dArrhythmias complicating other hospitalizations were not further adjudicated as SVT or VT but were considered to be predominantly SVT.

^eNot included in adjudication algorithm.