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. 2023 Nov 10;27(19):2850–2860. doi: 10.2174/0113862073257308231026073951

Fig. (2).

Fig. (2)

Construction and validation of the OESGs prognostic signature. (A) Coefficients of independent variables in LASSO regression. (B) Cross-validation of parameter selection in LASSO regression. (C) Forest plot of the OESGs model by stepwise Cox regression algorithm. RS = - 0.2310 × IL18RAP + 0.2303 × ECT2 - 0.1228 × PPARGC1A + 0.1809 × SCT2 + 0.0567 × NQO1. (D) Distribution of risk score and survival status in the internal (TCGA-LIHC) cohort. (E) Kaplan-Meier curve analyses for the high-risk and low-risk groups in the internal cohort. (F) The ROC curves of the OESGs prognostic signature at 1, 3, and 5 years in the internal cohort. (G) Distribution of risk score and survival status in the external (GSE14520) cohort. (H) Kaplan-Meier curve analyses for the high-risk and low-risk groups in the external cohort. (I) The ROC curves of the OESGs prognostic signature at 1, 3, and 5 years in the external cohort.