Table 6.
Association between diagnosis of SMI and recorded fragility fracture in women: age-specific HRs for women with SMI versus women without SMI
| Age, years | N | Unadjusted | Adjusted model 1a | Adjusted model 2b | |||
|---|---|---|---|---|---|---|---|
|
| |||||||
| HR | 95% CI | HR | 95% CI | HR | 95% CI | ||
| 50–54 | 78 593 | 1.40 | 1.23 to 1.60 | 1.36 | 1.19 to 1.55 | 1.35 | 1.18 to 1.56 |
| 55–59 | 30 515 | 1.77 | 1.53 to 2.05 | 1.77 | 1.53 to 2.05 | 1.73 | 1.49 to 2.02 |
| 60–64 | 25 978 | 1.52 | 1.30 to 1.76 | 1.50 | 1.29 to 1.74 | 1.48 | 1.26 to 1.73 |
| 65–69 | 24 116 | 1.52 | 1.32 to 1.74 | 1.52 | 1.32 to 1.75 | 1.49 | 1.29 to 1.71 |
| 70–74 | 22 338 | 1.37 | 1.20 to 1.57 | 1.36 | 1.18 to 1.55 | 1.32 | 1.15 to 1.52 |
| 75–79 | 21 517 | 1.43 | 1.24 to 1.64 | 1.43 | 1.24 to 1.64 | 1.41 | 1.23 to 1.62 |
| 80–84 | 19 587 | 1.81 | 1.57 to 2.08 | 1.82 | 1.58 to 2.09 | 1.80 | 1.56 to 2.08 |
| 85–99 | 20 157 | 1.64 | 1.41 to 1.91 | 1.63 | 1.40 to 1.90 | 1.61 | 1.38 to 1.88 |
a
Adjusted for Townsend and calendar year (6-year intervals).
b
Adjusted for Townsend, calendar year (6-year intervals), smoking, alcohol, and body mass index. Missing data on smoking, alcohol, and body mass index were handled with multiple imputation for bias correction. HR = hazard ratio. SMI = severe mental illness.