Fig. 6.

RosA induced the expression of Type II collagen, Aggrecan and Sox9 protein in DMM-induced OA mice model.

(A) The Sox9, Type II collagen, and Aggrecan, protein levels were assessed through Immunohistochemical staining in the cartilage of OA mice following i,a - injection of RosA, and (B) quantification was performed. Scale bars, 100 μm. Values are presented as the mean ± standard deviation. One-way analysis of variance followed by Bonferroni's test was used to determine significant differences. None significant (N.S), ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, #P < 0.05 compared to the Sham group.