Table 2.
Neuroradiological characteristics of the study population and bivariate comparison between patients with and without haemorrhagic transformation.
| Variable | Population (n = 194) | Haemorrhagic transformation | p-Value | |
|---|---|---|---|---|
| Yes (n = 28) | No (n = 166) | |||
| Microbleeds | 30 (15.5) | 6 (21) | 24 (12) | 0.2 |
| Cortical superficial siderosis | 1 (1) | 0 (0) | 1 (1) | 0.6 |
| Atrophy | 53 (31) | 7 (28) | 46 (31.5) | 0.7 |
| Perivascular spaces | 51 (27) | 6 (21) | 45 (27) | 0.5 |
| Lacunae | 104 (54) | 10 (36) | 94 (57) | 0.03 |
| White matter hyperintensity | 159 (83) | 21 (75) | 138 (84) | 0.3 |
| Number of acute lesions (>2) | 127 (66) | 21 (75) | 106 (65) | 0.4 |
| CT lesion volume, a cm3 | 0 (0–0.1) | 0.5 (0–2.9) | 0 (0–0.8) | <0.01 |
| MRI lesion volume, a cm3 | 2 (0.3–10) | 23.1 (8.5–58.1) | 1.3 (0.2–5.3) | <0.01 |
| Fazekas scale (deep white matter) | 0.2 | |||
| 0 | 40 (21) | 9 (32) | 31 (19) | |
| 1 | 109 (56.5) | 14 (50) | 95 (58) | |
| 2 | 35 (18) | 5 (18) | 30 (18) | |
| 3 | 9 (5) | 0 (0) | 9 (5.5) | |
| Fazekas scale (periventricular white matter) | 0.5 | |||
| 0 | 42 (22) | 8 (29) | 34 (21) | |
| 1 | 89 (46) | 14 (50) | 75 (45.5) | |
| 2 | 50 (26) | 5 (18) | 45 (27) | |
| 3 | 12 (6) | 1 (4) | 11 (7) | |
| CSVD score | 0.1 | |||
| 0 | 57 (29.5) | 13 (46) | 44 (27) | |
| 1 | 65 (34) | 8 (29) | 57 (34.5) | |
| 2 | 52 (27) | 5 (18) | 47 (28.5) | |
| 3 | 12 (6) | 0 (0) | 12 (7) | |
| 4 | 7 (4) | 2 (7) | 5 (3) | |
Unless specified, values are number of patients (%).
a
= median value (interquartile range).
Bold values denote statistical significance at the p < 0.05 level.
CSVD, cerebral small vessel disease; CT, computed tomography; MRI, magnetic resonance imaging.