TABLE 1.
Demographic and clinical characteristics of the sample.
| Parameter |
All N = 423 |
|---|---|
| Age, years | 57 ± 10 |
| Female, n (%) | 213 (50%) |
|
Race and ethnicity, n (%) Non‐Hispanic White Unknown |
421 (>99%) 2 (<1%) |
|
Education, n (%) No college degree College degree or higher |
148 (35%) 275 (65%) |
| APOE ε4 allele, n (%) | 95 (23%) |
| Interval between cognitive testing and PET Imaging, years | 0.2 ± 0.2 |
| Verbal memory a |
(N = 413) 0.00 ± 1.00 |
| Visual memory a |
(N = 419) 0.00 ± 1.00 |
| Attention/executive a |
(N = 406) 0.00 ± 1.00 |
| Language a |
(N = 394) 0.00 ± 1.00 |
| Visuospatial a |
(N = 419) 0.00 ± 1.00 |
| Global cognition a |
(N = 397) 0.00 ± 1.00 |
|
Aβ Centiloid, n (%) <20 20‐39 ≥40 |
(N = 403) 380 (94%) 14 (4%) 9 (2%) |
| Global Aβ, DVR |
(N = 414) 1.08 ± 0.11 |
| Entorhinal tau, SUVR |
(N = 322) 1.05 ± 0.09 |
| Rhinal tau, SUVR |
(N = 317) 1.10 ± 0.10 |
| Inferior temporal tau, SUVR |
(N = 322) 1.14 ± 0.08 |
| Middle temporal tau, SUVR |
(N = 322) 1.09 ± 0.08 |
| Fusiform tau, SUVR |
(N = 322) 1.14 ± 0.08 |
Note: Values represent mean ± standard deviation unless otherwise noted.
Abbreviations: Aβ, amyloid beta, APOE, apolipoprotein E, DVR, distribution volume ratio, PET, positron emission tomography, SUVR, standardized uptake value ratio.
Values standardized to z‐scores.