FIGURE 1.

Impact of APOE ε4 allele on hippocampal atrophy. (A) Illustration of the method used for measuring hippocampal dimensions. This measurement involves assessing the distance from the upper region of the hippocampus to the lower region of the hippocampus, or to the TB, as observed in MRI oblique coronal slices of the HH and HB. B, In the case of HH slices, APOE ε4 allele carriers exhibited greater height measurements from the left HH to the TB, as well as the height of the right HH, compared to non‐carriers. This difference in measurements highlights the more pronounced hippocampal atrophy observed in APOE ε4 carriers. APOE, apolipoprotein E; HB, hippocampal body; HH, hippocampal head; MRI, magnetic resonance imaging; TB, temporal bottom