TABLE 5.

Genome‐wide significant (p < 5 × 10⁻⁸) and suggestive (p < 1 × 10⁻⁶) variants associated with vascular dementia in cross‐ancestry meta‐analysis.

rsID	Nearest gene	Chr	Pos	EA/NEA	p value	MAF	Beta	SE
rs10119	TOMM40	19	45406673	G/A	1.21E‐17	0.2476	−0.327	0.054
rs4380108	MARCHF10	17	60893485	C/T	9.59E‐09	0.3127	−0.172	0.031
rs55747619	ITSN2	2	24530447	C/G	8.05E‐08	0.08706	−0.384	1.969
rs9379092	CAGE1	6	7344531	G/A	9.80E‐08	0.1172	−0.336	0.077
rs3757193	RPS6KA2	6	166923463	C/T	1.09E‐07	0.08347	2.151	0.636
rs3871399	CMTM7	3	32496413	C/G	2.61E‐07	0.124	0.550	0.640
rs17315346	BRINP2	1	177282235	C/T	2.67E‐07	0.01538	−2.412	5.17
rs1738249	DNAH8	6	38753960	C/T	2.86E‐07	0.3013	−0.050	0.040
rs12095469	OSBPL9	1	52206082	G/A	3.60E‐07	0.05292	3.654	3.513
rs4820650	ADRBK2	22	25925358	T/C	3.82E‐07	0.2468	0.050	0.054
rs61859886	MGMT	10	131353192	T/G	4.45E‐07	0.1528	−0.274	0.057
rs9857196	RYK	3	133830660	T/A	5.09E‐07	0.01997	3.438	2.670
rs637924	PCDH7	4	31465610	T/C	6.77E‐07	0.2564	−0.056	0.051
rs35810115	ZNF675	19	23780763	C/T	6.81E‐07	0.04992	−1.169	2.339
rs115331896	CRBN	3	3204942	T/G	6.95E‐07	0.01218	3.139	2.706
rs4401880	SLC18A1	8	19946066	C/T	7.20E‐07	0.3249	0.019	0.051
rs4823298	FBLN1	22	45915987	T/C	7.96E‐07	0.4581	0.029	0.0439
rs17335455	NXPH1	7	8853946	T/G	8.20E‐07	0.1633	−0.096	0.042
rs517484	RP11‐6N13.1	5	104490130	T/C	8.51E‐07	0.1965	−0.120	0.046
rs12814413	RBMS2	12	56916614	T/C	8.77E‐07	0.3514	0.050	0.051
rs4665372	CGREF1	2	27325837	T/A	9.19E‐07	0.3948	−0.104	0.043

Note: The meta‐analysis includes European, African, Asian, and Hispanic/Latino ancestries. Genome‐wide significant variants are highlighted in orange.

Abbreviation: MAF, minor allele frequency.