Table 2.
Univariate Logistic Regression Analysis of the Risk of Developing MAFLD
| Characteristics | B | SE | Wald χ2 | OR (95% CI) | P-value |
|---|---|---|---|---|---|
| Gender | 1.585 | 0.060 | 706.34 | 4.88 (4.34–5.49) | <0.001*** |
| Age | 0.048 | 0.003 | 344.24 | 1.05 (1.04–1.06) | <0.001*** |
| Alcohol drinking | 0.921 | 0.056 | 269.48 | 2.51 (2.25–2.81) | <0.001*** |
| Smoking | 1.024 | 0.063 | 263.95 | 2.79 (2.46–3.15) | <0.001*** |
| LAP | 0.061 | 0.002 | 1132.88 | 1.06 (1.06–1.07) | <0.001*** |
| VAI | 0.888 | 0.032 | 767.15 | 2.43 (2.28–2.59) | <0.001*** |
| CMI | 2.720 | 0.090 | 921.43 | 15.18 (12.74–18.09) | <0.001*** |
| TyG | 2.487 | 0.070 | 1245.73 | 12.03 (10.48–13.81) | <0.001*** |
| BAI | 0.133 | 0.008 | 255.25 | 1.14 (1.12–1.16) | <0.001*** |
| HSI | 0.368 | 0.010 | 1381.54 | 1.45 (1.42–1.47) | <0.001*** |
| FLI | 0.075 | 0.002 | 1598.49 | 1.08 (1.07–1.08) | <0.001*** |
| BMI | 0.553 | 0.015 | 1332.50 | 1.74 (1.69–1.79) | <0.001*** |
| WC (cm) | 0.193 | 0.005 | 1386.43 | 1.21 (1.20–1.23) | <0.001*** |
| WHtR | 1.478 | 0.038 | 1490.75 | 4.39 (4.07–4.73) | <0.001*** |
| SBP (mmHg) | 0.055 | 0.002 | 637.45 | 1.06 (1.05–1.06) | <0.001*** |
| DBP (mmHg) | 0.077 | 0.003 | 672.06 | 1.08 (1.07–1.09) | <0.001*** |
| ALT (IU/L) | 0.064 | 0.002 | 727.43 | 1.07 (1.06–1.07) | <0.001*** |
| AST (IU/L) | 0.072 | 0.004 | 355.06 | 1.07 (1.07–1.08) | <0.001*** |
| GGT (IU/L) | 0.035 | 0.002 | 513.22 | 1.04 (1.03–1.04) | <0.001*** |
| ALP (IU/L) | 0.028 | 0.001 | 362.64 | 1.03 (1.03–1.03) | <0.001*** |
| TG (mmol/L) | 1.344 | 0.046 | 853.24 | 3.84 (3.51–4.20) | <0.001*** |
| LDL (mmol/L) | 0.911 | 0.044 | 421.74 | 2.49 (2.28–2.71) | <0.001*** |
| HDL (mmol/L) | −3.313 | 0.122 | 736.36 | 0.04 (0.03–0.05) | <0.001*** |
| TC (mmol/L) | 0.521 | 0.031 | 285.78 | 1.68 (1.59–1.79) | <0.001*** |
| FPG (mmol/L) | 0.984 | 0.050 | 392.02 | 2.67 (2.43–2.95) | <0.001*** |
| TBIL (umol/L) | 0.018 | 0.006 | 9.88 | 1.02 (1.01–1.03) | 0.002** |
| DBIL (umol/L) | 0.034 | 0.030 | 1.33 | 1.04 (0.98–1.10) | 0.249 |
| IBIL (umol/L) | 0.023 | 0.007 | 11.72 | 1.02 (1.01–1.04) | 0.001** |
| TBA (mmol/L) | 0.021 | 0.014 | 2.20 | 1.02 (0.99–1.05) | 0.138 |
| UA (umol/L) | 0.011 | 0 | 829.27 | 1.01 (1.01–1.01) | <0.001*** |
| Alb (g/L) | 0.045 | 0.011 | 15.90 | 1.05 (1.02–1.07) | <0.001*** |
| TP (g/L) | 0.015 | 0.007 | 4.58 | 1.02 (1.00–1.03) | 0.032* |
| G (g/L) | −0.004 | 0.008 | 0.20 | 1.00 (0.98–1.01) | 0.655 |
| HGB (g/L) | 0.052 | 0.002 | 638.02 | 1.05 (1.05–1.06) | <0.001*** |
| WBC (10^9/L) | 0.303 | 0.020 | 240.91 | 1.35 (1.30–1.41) | <0.001*** |
| PLT (10^9/L) | 0.001 | 0 | 7.36 | 1.00 (1.00–1.00) | 0.007** |
Notes: Assignment of categorical variables, Gender (Female: 0, Male: 1); Drinking (No: 0, Yes: 1); Smoking (No: 0, Yes: 1). WHtR was used as a continuity variable according to the grouping (WHtR1-WHtR4). *P<0.05, **P<0.01,***P<0.001.
Abbreviations: SBP, Systolic blood pressure; DBP, diastolic blood pressure; GGT, gamma glutamyl transferase; ALP, alkaline phosphatase; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol; FPG, fasting plasma glucose; TBIL, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin; UA, uric acid; Alb, albumin; TP, total protein; G, globulin; HGB, hemoglobin; WBC, white blood cells; PLT, platelet count; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBA, total bile acids; BMI, body mass index; WC, waist circumference index; WHtR, waist to height ratio; HSI, hepatic steatosis index; TyG, triglyceride-glucose index; BAI, body adiposity index; LAP, accumulation product; VAI, visceral fat index; CMI, lipid cardiometabolic index; FLI, fatty liver index.