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. 2001 Aug;75(16):7462–7469. doi: 10.1128/JVI.75.16.7462-7469.2001

TABLE 2.

Amino acid positions associated with reduced in vitro susceptibility to PIs in combined panel of viral isolates

Inhibitor Amino acid positions associated with reduced susceptibilitya at:
P < 0.0062 0.0062 < P < 0.05
Lopinavir 54, 82, 10, 71, 46, 20, 90, 84, 24, 53, 63 73, 43, 93, 58, 33, 12
IDV 10, 54, 82, 46, 90, 93, 71, 84, 20, 73, 63 24, 53, 58, 62, 60
NFV 10, 90, 54, 71, 84, 20, 73, 88, 93, 46, 33 82, 19, 77, 63
RTV 54, 82, 10, 90, 84, 63, 71, 20, 24, 53, 46, 73 43, 33, 93, 58, 14
SQV 90, 10, 84, 71, 73, 54, 63, 20 53, 19, 33, 93, 48, 67
a

Ordered from greatest to least degree of significance (Wilcoxon rank sum test). 

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