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. 2024 Apr 27;78(7):393–404. doi: 10.1111/pcn.13671

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© 2024 The Authors. Psychiatry and Clinical Neurosciences published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Psychiatry and Neurology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Fig. 3 — The association between RA and global brain structure, mediation analysis of the association between RA, global brain structures, and processing speed. (a) shows the significant association of RA with global brain structure (white matter volumes and cortical surface areas). (b) shows the mediating effect of global brain structure in the association of RA and processing speed. DE, direct effect; IE, indirect effect; lh, left hemisphere; Prop.med, proportion of mediation; rh, right hemisphere; RA, relative amplitude.