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. 2024 Apr 27;78(7):393–404. doi: 10.1111/pcn.13671

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© 2024 The Authors. Psychiatry and Clinical Neurosciences published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Psychiatry and Neurology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Fig. 4 — The association of RA with regional brain structures and white matter microstructures. (a–c) show the association of RA with regional brain structures (a) cortical volume, cortical surface area, cortical thickness; (b) subcortical volume and subcortical intensity; (c) FA and MD. (d) shows the significant mediating effect of regional brain structures in the association of RA and processing speed. (e) shows the significant mediating effect of white matter microstructures in the association of RA and processing speed. ATR, anterior thalamic radiation; CC, corpus callosum; DE, direct effect; FA, fractional anisotropy; FM, forceps minor; IE, indirect effect; lh, left hemisphere; MD, mean diffusivity; Prop.med, proportion of mediation; PTR, posterior thalamic radiation; RA, relative amplitude; rh, right hemisphere; SLF, superior longitudinal fasciculus; STR, superior thalamic radiation; Ventral DC, Ventral Diencephalon; vol, volume.