Table 2.
Genes upregulated by AUD related to epidermal differentiation
| Gene Name | Log 2 Fold Change | Adj. P Value |
|---|---|---|
| ABCA12 | 2.09 | 0.02 |
| CALML5 | 4.57 | 0 |
| CRNN | 7.32 | 0 |
| EMP1 | 2.29 | 0.03 |
| EREG | 2.2 | 0 |
| FLG2 | 5.11 | 0.04 |
| GRHL3 | 2.27 | 0 |
| KLK6 | 3.85 | 0.01 |
| KLK7 | 3.75 | 0 |
| KRT10 | 1.66 | 0.05 |
| KRT13 | 3.87 | 0.03 |
| KRT16 | 3.23 | 0.02 |
| KRT24 | 8.36 | 0 |
| KRT4 | 3.63 | 0 |
| KRT6B | 3.79 | 0 |
| KRT6C | 3.27 | 0 |
| KRT78 | 6.64 | 0 |
| SCEL | 2.42 | 0.01 |
| SPINK5 | 4.83 | 0 |
| SPINK7 | 5.66 | 0.05 |
| SPRR1A | 6.23 | 0 |
| SPRR1B | 4.06 | 0 |
| SPRR2A | 5.96 | 0 |
| SPRR2D | 5.62 | 0 |
| SPRR2E | 5.68 | 0 |
| SPRR3 | 7.59 | 0 |
| TGM1 | 2.73 | 0.02 |
Alphabetically sorted list of genes enriched in alcohol use disorder (AUD) cells, as determined by gene ontology (GO) analysis for GO:0030216: keratinocyte differentiation, GO:0008544: epidermis development, GO:0031424: keratinization, GO:0018149: peptide cross-linking, GO:0061436: establishment of skin barrier.