FIGURE 1.

Trends over time for quarterly adjusted mortality rates by drug (2010‒2017). Overall buprenorphine involved deaths rates are lower than that of oxycodone, hydrocodone, and methadone. Buprenorphine population‐adjusted rates had an identified joinpoint at 2016Q3; whereas,) no joinpoint was identified in utilization‐adjusted rates. Trends are displayed on log‐transformed rate scale to show percent change over time. Dispensing data available beginning in 2010Q3; methadone dosage units dispensed mortality rates not shown due to known underestimate of methadone dispensing in data.