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. 2023 Oct 27;14(12):3322–3338. doi: 10.1007/s13346-023-01456-y

Fig. 8.

Fig. 8

In vivo efficacy studies in a GL261 GBM-resected mouse model. A Schematic diagram of the timeline of orthotopic tumor inoculation, resection, and treatment administration. DOXC12 was locally administered at a dose of 5 mg/kg (5 μL of DOXC12-LNCCL hydrogel, 20 mg/mL). Ibuprofen was systemically administered post-surgery and every 24 h for 3 days at a dose of 30 mg/kg. B The Kaplan–Meier survival curves of mice treated with different interventions