. 2023 Oct 27;14(12):3322–3338. doi: 10.1007/s13346-023-01456-y

Table 2.

In vivo efficacy studies in a GL261 resected mouse model: median survival (days), numbers of long-term survivors in each group, and statistical analysis

Treatment	Median survival (days)	Long-term survivors	Log-rank test
Resected	29	0/8
Blank LNC^CL	29	0/6	ns (vs resected)
Ibuprofen	28.5	0/8	ns (vs resected) ns (vs blank LNC^CL)
DOXC₁₂-LNC^CL	37	3/9	ns (vs resected) ** (vs blank LNC^CL)
DOXC₁₂-LNC^CL + Ibuprofen	42	2/8	* (vs resected) ** (vs blank LNC^CL)

Log-rank (Mantel-Cox) test: survival curve comparison between groups

*p < 0.05, **p < 0.01, n 6–9 mice per group