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. 2024 Aug 15;35(11):1989–1998. doi: 10.1007/s00198-024-07224-z

Table 2.

Association between baseline risk factors and fracture: compare the regression coefficients between the conventional Cox’s proportional hazard model with no competing risk adjustment, and the competing risk models, including the cause-specific model, the Fine-Gray model, and the multistate model

Model with no competing risk adjustment Model with competing risk adjustment
Conventional Cox’s proportional hazard model Cause-specific model Fine-Gray model Multistate model
Outcome of interest Fracture Fracture Death Fracture Fracture
Predictors
Sex (women)

1.44

(1.19, 1.74)

1.44

(1.19, 1.74)

0.58

(0.49, 0.68)

1.72

(1.45, 2.04)

1.44

(1.19, 1.74)

Age (+ 1 year)

1.03

(1.02, 1.05)

1.03

(1.02, 1.05)

1.13

(1.11, 1.14)

0.99

(0.98, 1.01)

1.03

(1.02, 1.05)

Femoral neck bone mineral density T-score (− 1)

1.50

(1.38, 1.63)

1.50

(1.38, 1.63)

0.99

(0.91, 1.07)

1.41

(1.32, 1.51)

1.50

(1.38, 1.63)

History of falls in the last 12 months

1.07

(0.94, 1.22)

1.07

(0.94, 1.23)

0.77

(0.66, 0.91)

1.20

(1.07, 1.35)

1.07

(0.94, 1.23)

Prior fracture after the age of 50 years prior to recruitment

1.92

(1.56, 2.37)

1.92

(1.56, 2.37)

1.25

(0.95, 1.63)

1.62

(1.35, 1.95)

1.92

(1.56, 2.37)

Discriminative performance
C-statistic (95% CI)

0.70

(0.68, 0.72)

0.70

(0.68, 0.72)

0.73

(0.71, 0.75)

0.68

(0.66, 0.70)

0.71

(0.70, 0.73)

Data presented as hazard ratios (95% CI), unless otherwise indicated