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. 2024 Oct 23;14:25103. doi: 10.1038/s41598-024-76933-6

Fig. 2.

Fig. 2

MRI phenotype MYCN-amplified RB1 wild-type (MYCNampRB1+/+) retinoblastoma versus RB1 pathogenic variation (RB1−/−) retinoblastoma. (A) Axial 2D T2-weighted MR image of a 42-month-old patient with MYCNampRB1+/+ retinoblastoma. The tumor has a diffuse growth pattern and is plaque shaped. Also, the intensity in the tumor varies greatly. (B) Axial 2D T2-weighted MR image of a 35-month-old patient with RB1−/− retinoblastoma. The tumor has an endophytic growth pattern and is dome shaped.