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. 2024 Oct 23;14:448. doi: 10.1038/s41398-024-03167-5

Fig. 2. Lingo2 expression level is increased in the Maternally VPA-treated neuron.

Fig. 2

A Volcano plot of the quantitative comparison between the secretomes of maternal VPA treated and Saline treated neurons of 3 experiments identified 145 proteins. Secretome proteins that are significantly changed are marked as red dots. Significantly changed protein: p < 0.05 (-log10 > 1.3). B Immunoblot analysis of mouse primary neurons obtained from maternal VPA-treated pups. C Quantification of Lingo2 protein level in C (n = 6, Mean ± SEM). Lingo2 protein level was increased in maternal VPA-treated neurons. D Quantification of Lingo2 mRNA level (n = 5, Mean ± SEM). Lingo2 mRNA level was unchanged in maternal VPA-treated neurons.