TABLE 3.
HA activity of hinge and RGD mutant viruses
| Virus | Mutation | HA activity
|
|
|---|---|---|---|
| Optimal pH | HA titera | ||
| CDV-1-51 | None | 6.6 | 160 |
| BHv1 | E-277 (S→I) | NAb | <2 |
| BHv2 | E-277 (S→N) | 6.6 | 320 |
| CDV-1-51v1 | E-277 (S→I) | NA | <2 |
| CDV-1-51v2 | E-277 (S→N) | 6.6 | 320 |
| CDV-1-51v3 | E-277 (S→V) | 6.8 | 40 |
| CDV-1-51v4 | E-277 (S→P) | 6.8 | 40 |
| CDV-1-51v5 | E-390 (D→N) | 6.6 | 160 |
| CDV-1-51v6 | E-390 (D→E) | 6.6 | 320 |
| CDV-1-51v7 | E-390 (D→Y) | 6.6 | 160 |
a
HA titer is expressed as the reciprocal of the highest dilution of virus which yielded complete agglutination of gander RBCs.
b
NA, not applicable.