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Normalized sensitivity coefficients (NSCs) of optimized parameters using the area under curves (AUCs) of F-53B in (A) plasma, liver, and placenta in the pregnant mice, and (B) plasma, brain, and liver in the fetal mice after a single oral dose of 80 μg/kg/day on GD13. Only parameters with NSC ≥ 0.3 are shown in the plots.
