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. Author manuscript; available in PMC: 2024 Oct 24.
Published in final edited form as: J Fluor Chem. 2023 Feb 21;267:110106. doi: 10.1016/j.jfluchem.2023.110106

Fig. 7.

Fig. 7.

3rd-Generation DFV-taxoids in the β-tubulin binding site. The fluorine interactions of the DFV group with the π-system of Phe272 and H-bonding with Ser236 for (A) 11e-05 and (B) 11f-06. H-bonding interactions of the OCF3 group of 11e-05 (C) and the OCF2H group of 11f-06 (D) with His229. Adapted from Ref. [33] with permission.